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Pet CBD oils and other pet CBD products have become incredibly popular among pet owners. It’s easy to see why, since so many pet owners have found that CBD has had a positive impact on their pet’s quality of life. Pet owners often use CBD to help their pet’s anxiety, sleep, pain, or behavior, and many say it’s extremely beneficial. However, if you’re a pet owner who is thinking of trying pet CBD for the first time, there’s one very important thing you need to consider: mixing pet CBD with other medications.

Many people don’t know that CBD can interact with certain medications. CBD can interact with certain medications for humans and it can also interact with certain pet medications. Below, we’ll talk about why CBD interacts with certain medications, which medications CBD may interact with, and why it’s always a good idea to talk to your veterinarian before trying pet CBD.

Why CBD May Interact With Certain Medications

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Cannabidiol (CBD) can interact with some medications because of the way it affects the liver. On its own, CBD is thought to be quite safe for the liver. But CBD can inhibit a certain group of liver enzymes called cytochrome P450 enzymes, which can affect the performance of certain medications. Essentially, some medications need to be metabolized by P450 enzymes. So when CBD inhibits these enzymes, some drugs cannot be properly metabolized. In some cases, this leads to build up, which means the effects of the drug will last longer. In other cases, this impaired metabolizing means that the drug becomes less effective since it’s not being properly processed by the body’s P450 enzymes.

CBD is far from the only thing that can inhibit P450 enzymes. Some natural foods also inhibit P450 enzymes, as do some supplements. Perhaps the most well-known substance that interacts with P450 enzymes is grapefruit.

Which Medications Could CBD Oils and CBD Products Interact With?

So, CBD can interact with certain medications because it inhibits P450 enzymes. But which medications can CBD interact with? Below, we’ll feature a list of common types of medications that are affected when P450 enzymes are inhibited. Please note that this is just an example list of drug interactions and that other medications may require the use of P450 enzymes.

Common Medications That May Interact With CBD

  • NSAIDS
  • Antihistamines
  • Steroids
  • Benzodiazepines (Including Diazepam)
  • Fentanyl
  • Anesthetics
  • Certain Antibiotics

Listed above are some categories of medications that may interact with CBD, which should give you a general idea of the types of medications that CBD may interact with. For pet medications specifically, we do also want to call out a few common prescription drugs for pets that can interact with CBD: Prednisone, Tramadol, Meloxicam, and Gabapentin. As with the list above, please note that this is not a complete list of all pet medications that may interact with CBD.

Talking to Your Veterinarian About Trying Pet CBD

We recommend that all pet owners talk to their veterinarian before trying pet CBD– or any type of supplement, for that matter. It’s always important to consult a provider of veterinary medicine before adding new supplements to your pet’s routine since many supplements can interact with prescription medications. If your pet is taking a prescription medication that interacts with a particular supplement, your veterinarian may sometimes discourage using it. Or, they may approve its use, but recommend taking that supplement at a different time of day from the prescription medication.

Final Thoughts on Mixing CBD With Other Medications

CBD is something that many pet owners say has provided life-changing health benefits for their pets. Many pet owners have tried CBD oil and other CBD products for its potential anti-inflammatory properties or to help with their pet’s pain, anxiety, behavior, and the list goes on. CBD also has almost no negative side effects when it’s used on its own. The only known side effect of CBD is drowsiness, and even that only occurs at extremely high doses. But we always recommend that you talk to your veterinarian before giving your pet CBD for the first time since CBD can interact with certain medications. It’s always best to consult your veterinarian before trying any new supplement so you can make sure your pet is getting the best possible care.

If, after you’ve consulted with your veterinarian, you decide that CBD is right for your pet, we welcome you to check out our range of high quality CBD products for pets. All of our pet CBD products are veterinarian-formulated and veterinarian-approved. The CBD we use in our pet products is full-spectrum CBD that has been CO2 extracted from hemp plants grown right here in the United States. This premium quality CBD is also third party lab tested, so you can always be sure your pet is getting an accurate dose of CBD and little to no tetrahydrocannabinol (THC). In addition to using high quality CBD within our CBD pet products, we use premium quality, pet healthy ingredients to make the rest of our CBD tinctures, dog CBD treats, and other CBD products. Our organic, non-GMO CBD pet products are made using healthy and delicious ingredients (like salmon oil and pumpkin) that offer your pets additional health benefits.

Dr. Jay You

Dr. Jay You

Dr. You is a veterinarian with 6+ years of experience that has witnessed firsthand with his patients the benefits of CBD in the veterinary industry. Whether it be for anxiety, arthritic pain, or other problems, a growing number of his patients have turned to CBD as a holistic alternative with budding success. Dr. You believes in the future of CBD and is committed to advancing its place in the veterinary world.